The accident occurred at kilometre 12 along Benin-Sapele-Warri express road.
It was learnt the students were going to Delta State to attend the funeral ceremony of a grandmother of one of their colleague.
Three died on the spot while one among the five injured died at the Benin Central Hospital.
One of the victims who gave his name as Collins said they were 14 inside the vehicle including the driver.
Collins said they had a burst tyre which made the vehicle to somersault.
Sector Commander of the Federal Road Safety Corps (FRSC) Mr. Luka Ikpi who confirmed the accident attributed it to over speeding and loss of control.
He said three persons died and five injured were rescued and taken to the hospital.
Meanwhile, a primary six pupil of Emokpa Primary School along Upper Forestry road was also Friday electrocuted.
The pupil was said to be picking dirt’s as a punishment for coming late to school when he mistakenly held onto an exposed wire.
Witnesses said the wire was cut-off by a wind that accompanied the recent rain.
The body has been deposited at a mortuary but police spokesman, DSP Moses Eguaveon could not be reached for comments.